Chimerix, Inc.
April 16, 2013

Chimerix Announces Completion of Initial Public Offering and Exercise of Underwriters' Over-allotment Option

RESEARCH TRIANGLE PARK, N.C., April 16, 2013 (GLOBE NEWSWIRE) -- Chimerix, Inc. (Nasdaq:CMRX), a biopharmaceutical company developing novel, oral antivirals in areas of high unmet medical need, announced today the completion of its initial public offering of 8,418,000 shares of its common stock at an initial public offering price of $14.00 per share. This includes the exercise in full by the underwriters of their option to purchase up to 1,098,000 additional shares of common stock. Chimerix's common stock is listed on the NASDAQ Global Market under the trading symbol "CMRX." Chimerix expects to use the net proceeds from the offering primarily for research and development expenses related to CMX001, as well as for general corporate purposes.

Morgan Stanley and Cowen and Company acted as joint book-running managers for the offering. William Blair and Lazard Capital Markets acted as co-managers.

A registration statement relating to these securities was declared effective by the Securities and Exchange Commission on April 10, 2013. This offering was made solely by means of a prospectus. A copy of the final prospectus relating to the offering may be obtained by contacting Morgan Stanley & Co. LLC, Attn: Prospectus Department, 180 Varick Street, 2nd Floor, New York, NY 10014, or by calling toll free 1-866-718-1649 or emailing at prospectus@morganstanley.com; or Cowen and Company, LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, Attn: Prospectus Department, by calling (631) 274-2806, or faxing (631) 254-7140.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or other jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or other jurisdiction.

About Chimerix and CMX001

Chimerix is committed to the discovery, development and commercialization of novel, oral antiviral therapeutics designed to transform patient care in areas of high unmet medical need. The Company's proprietary lipid technology has given rise to two clinical-stage lipid acyclic nucleoside phosphonates, CMX001 and CMX157, which have demonstrated the potential for enhanced activity and safety in convenient, orally administered dosing regimens.

Chimerix's lead product candidate, CMX001, is a broad spectrum, oral nucleotide analog lipid-conjugate that blocks replication of double-stranded DNA (dsDNA) viruses, including cytomegalovirus (CMV), adenovirus (AdV), BK virus and herpes simplex virus. CMX001 has completed Phase 2 clinical development for the prevention of CMV in hematopoietic stem cell transplant (HSCT) recipients. Chimerix is also conducting a Phase 2 study in HSCT recipients which is evaluating CMX001 as a preemptive therapy for AdV disease, an often-fatal infection which has no approved therapies. Since 2009, Chimerix has made CMX001 available under expanded access regulations to over 80 transplant centers worldwide for the treatment of over 430 patients with life-threatening dsDNA viral infections. Chimerix anticipates initiating SUPPRESS, its Phase 3 study of CMX001 for the prevention of CMV infection in adults undergoing HSCT, in 2013.

Chimerix is also developing CMX001 as a potential medical countermeasure against smallpox under a contract from the Biomedical Advanced Research and Development Authority (BARDA).

Chimerix's second product candidate, CMX157, an oral nucleotide analog lipid-conjugate in Phase 1 development for the treatment of HIV infection, was licensed to Merck in July 2012.

CONTACT: CHIMERIX CONTACTS:

         Rebecca Heath, 919.972.7124

         Elizabeth Kelly, 919.972.7109



         MEDIA CONTACT:

         Tony Plohoros

         908.940.0135

         tplohoros@6degreespr.com



         INVESTOR CONTACT:

         Lillian Stern

         212.362.1200

         lilian@sternir.com
Source: Chimerix, Inc.

News Provided by Acquire Media